Queuine links translational control in eukaryotes to a micronutrient from bacteria

In eukaryotes, the wobble position of tRNA with a GUN anticodon is modified to the 7-deaza-guanosine derivative queuosine (Q34), but the original source of Q is bacterial, since Q is synthesized by eubacteria and salvaged by eukaryotes for incorporation into tRNA. Q34 modification stimulates Dnmt2/P...

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Detalles Bibliográficos
Autores principales: Müller, Martin, Legrand, Carine, Tuorto, Francesca, Kelly, Vincent P, Atlasi, Yaser, Lyko, Frank, Ehrenhofer-Murray, Ann E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468285/
https://www.ncbi.nlm.nih.gov/pubmed/30715423
http://dx.doi.org/10.1093/nar/gkz063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468285/
https://www.ncbi.nlm.nih.gov/pubmed/30715423
http://dx.doi.org/10.1093/nar/gkz063

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