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Queuine links translational control in eukaryotes to a micronutrient from bacteria
In eukaryotes, the wobble position of tRNA with a GUN anticodon is modified to the 7-deaza-guanosine derivative queuosine (Q34), but the original source of Q is bacterial, since Q is synthesized by eubacteria and salvaged by eukaryotes for incorporation into tRNA. Q34 modification stimulates Dnmt2/P...
Autores principales: | Müller, Martin, Legrand, Carine, Tuorto, Francesca, Kelly, Vincent P, Atlasi, Yaser, Lyko, Frank, Ehrenhofer-Murray, Ann E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468285/ https://www.ncbi.nlm.nih.gov/pubmed/30715423 http://dx.doi.org/10.1093/nar/gkz063 |
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