Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA‐Binding Polyamide Analogues

A combined structural and quantitative biophysical profile of the DNA binding affinity, kinetics and sequence‐selectivity of hairpin polyamide analogues is described. DNA duplexes containing either target polyamide binding sites or mismatch sequences are immobilized on a microelectrode surface. Quan...

Descripción completa

Detalles Bibliográficos
Autores principales: Aman, Khalid, Padroni, Giacomo, Parkinson, John A., Welte, Thomas, Burley, Glenn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468288/
https://www.ncbi.nlm.nih.gov/pubmed/30407668
http://dx.doi.org/10.1002/chem.201805338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468288/
https://www.ncbi.nlm.nih.gov/pubmed/30407668
http://dx.doi.org/10.1002/chem.201805338

Ejemplares similares