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Secretion of an Argonaute protein by a parasitic nematode and the evolution of its siRNA guides

Extracellular RNA has been proposed to mediate communication between cells and organisms however relatively little is understood regarding how specific sequences are selected for export. Here, we describe a specific Argonaute protein (exWAGO) that is secreted in extracellular vesicles (EVs) released...

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Detalles Bibliográficos
Autores principales: Chow, Franklin Wang-Ngai, Koutsovoulos, Georgios, Ovando-Vázquez, Cesaré, Neophytou, Kyriaki, Bermúdez-Barrientos, Jose R, Laetsch, Dominik R, Robertson, Elaine, Kumar, Sujai, Claycomb, Julie M, Blaxter, Mark, Abreu-Goodger, Cei, Buck, Amy H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468290/
https://www.ncbi.nlm.nih.gov/pubmed/30820541
http://dx.doi.org/10.1093/nar/gkz142