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Structural basis for DNA recognition by FOXC2

The FOXC family of transcription factors (FOXC1 and FOXC2) plays essential roles in the regulation of embryonic, ocular, and cardiac development. Mutations and abnormal expression of FOXC proteins are implicated in genetic diseases as well as cancer. In this study, we determined two crystal structur...

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Detalles Bibliográficos
Autores principales: Chen, Xiaojuan, Wei, Hudie, Li, Jun, Liang, Xujun, Dai, Shuyan, Jiang, Longying, Guo, Ming, Qu, Lingzhi, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468292/
https://www.ncbi.nlm.nih.gov/pubmed/30722065
http://dx.doi.org/10.1093/nar/gkz077