Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor

Upon triggering by their inducer, signal transduction ATPases with numerous domains (STANDs), initially in monomeric resting forms, multimerize into large hubs that activate target macromolecules. This process requires conversion of the STAND conserved core (the NOD) from a closed form encasing an A...

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Detalles Bibliográficos
Autores principales: Lisa, María-Natalia, Cvirkaite-Krupovic, Virginija, Richet, Evelyne, André-Leroux, Gwenaëlle, Alzari, Pedro M, Haouz, Ahmed, Danot, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468293/
https://www.ncbi.nlm.nih.gov/pubmed/30788511
http://dx.doi.org/10.1093/nar/gkz112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468293/
https://www.ncbi.nlm.nih.gov/pubmed/30788511
http://dx.doi.org/10.1093/nar/gkz112

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