Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase

The integration of the retroviral genome into the chromatin of the infected cell is catalysed by the integrase (IN)•viral DNA complex (intasome). This process requires functional association between the integration complex and the nucleosomes. Direct intasome/histone contacts have been reported to m...

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Detalles Bibliográficos
Autores principales: Mauro, Eric, Lesbats, Paul, Lapaillerie, Delphine, Chaignepain, Stephane, Maillot, Benoit, Oladosu, Oyindamola, Robert, Xavier, Fiorini, Francesca, Kieffer, Bruno, Bouaziz, Serge, Gouet, Patrice, Ruff, Marc, Parissi, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468294/
https://www.ncbi.nlm.nih.gov/pubmed/30767014
http://dx.doi.org/10.1093/nar/gkz091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468294/
https://www.ncbi.nlm.nih.gov/pubmed/30767014
http://dx.doi.org/10.1093/nar/gkz091

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