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Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase
The integration of the retroviral genome into the chromatin of the infected cell is catalysed by the integrase (IN)•viral DNA complex (intasome). This process requires functional association between the integration complex and the nucleosomes. Direct intasome/histone contacts have been reported to m...
Autores principales: | Mauro, Eric, Lesbats, Paul, Lapaillerie, Delphine, Chaignepain, Stephane, Maillot, Benoit, Oladosu, Oyindamola, Robert, Xavier, Fiorini, Francesca, Kieffer, Bruno, Bouaziz, Serge, Gouet, Patrice, Ruff, Marc, Parissi, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468294/ https://www.ncbi.nlm.nih.gov/pubmed/30767014 http://dx.doi.org/10.1093/nar/gkz091 |
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