A multi-axial RNA joint with a large range of motion promotes sampling of an active ribozyme conformation

Investigating the dynamics of structural elements in functional RNAs is important to better understand their mechanism and for engineering RNAs with novel functions. Previously, we performed rational engineering studies with the Varkud satellite (VS) ribozyme and switched its specificity toward non-...

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Detalles Bibliográficos
Autores principales: Girard, Nicolas, Dagenais, Pierre, Lacroix-Labonté, Julie, Legault, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468304/
https://www.ncbi.nlm.nih.gov/pubmed/30993347
http://dx.doi.org/10.1093/nar/gkz098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468304/
https://www.ncbi.nlm.nih.gov/pubmed/30993347
http://dx.doi.org/10.1093/nar/gkz098

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