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Structural organization of a Type III-A CRISPR effector subcomplex determined by X-ray crystallography and cryo-EM

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated Cas proteins provide an immune-like response in many prokaryotes against extraneous nucleic acids. CRISPR–Cas systems are classified into different classes and types. Class 1 CRISPR–Cas systems form multi-protein...

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Detalles Bibliográficos
Autores principales: Dorsey, Bryan W, Huang, Lei, Mondragón, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468305/
https://www.ncbi.nlm.nih.gov/pubmed/30759237
http://dx.doi.org/10.1093/nar/gkz079