Stereocontrolled Synthesis of 1,4‐Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals

We report a visible‐light‐mediated organocatalytic strategy for the enantioselective acyl radical conjugate addition to enals, leading to valuable 1,4‐dicarbonyl compounds. The process capitalizes upon the excited‐state reactivity of 4‐acyl‐1,4‐dihydropyridines that, upon visible‐light absorption, c...

Descripción completa

Detalles Bibliográficos
Autores principales: Goti, Giulio, Bieszczad, Bartosz, Vega‐Peñaloza, Alberto, Melchiorre, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468318/
https://www.ncbi.nlm.nih.gov/pubmed/30419156
http://dx.doi.org/10.1002/anie.201810798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468318/
https://www.ncbi.nlm.nih.gov/pubmed/30419156
http://dx.doi.org/10.1002/anie.201810798

Ejemplares similares