Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer

Studies of alterations in histone methylation in cancer have led to the identification of histone methyltransferases and demethylases as novel targets for therapy. Lysine-specific demethylase 1 (LSD1, also known as KDM1A), demethylates H3K4me1/2, or H3K9me1/2 in a context-dependent manner. In additi...

Descripción completa

Detalles Bibliográficos
Autores principales: Majello, Barbara, Gorini, Francesca, Saccà, Carmen Daniela, Amente, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468368/
https://www.ncbi.nlm.nih.gov/pubmed/30866496
http://dx.doi.org/10.3390/cancers11030324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468368/
https://www.ncbi.nlm.nih.gov/pubmed/30866496
http://dx.doi.org/10.3390/cancers11030324

Ejemplares similares