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Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer

Studies of alterations in histone methylation in cancer have led to the identification of histone methyltransferases and demethylases as novel targets for therapy. Lysine-specific demethylase 1 (LSD1, also known as KDM1A), demethylates H3K4me1/2, or H3K9me1/2 in a context-dependent manner. In additi...

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Detalles Bibliográficos
Autores principales:	Majello, Barbara, Gorini, Francesca, Saccà, Carmen Daniela, Amente, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468368/ https://www.ncbi.nlm.nih.gov/pubmed/30866496 http://dx.doi.org/10.3390/cancers11030324

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