Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

The common conception of intrinsically disordered proteins (IDPs) is that they stochastically sample all possible configurations driven by thermal fluctuations. This is certainly true for many IDPs, which behave as swollen random coils that can be described using polymer models developed for homopol...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Ucheor B., Sanabria, Hugo, Smirnova, Tatyana, Bowen, Mark E., Weninger, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468417/
https://www.ncbi.nlm.nih.gov/pubmed/30909517
http://dx.doi.org/10.3390/biom9030114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468417/
https://www.ncbi.nlm.nih.gov/pubmed/30909517
http://dx.doi.org/10.3390/biom9030114

Ejemplares similares