Combination Therapy of Chloroquine and C(2)-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells

Non-small cell lung cancer (NSCLC) is a type of malignant cancer, and 85% of metastatic NSCLC patients have a poor prognosis. C(2)-ceramide induces G2/M phase arrest and cytotoxicity in NSCLC cells. In this study, the autophagy-inducing effect of C(2)-ceramide was demonstrated, and cotreatment with...

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Detalles Bibliográficos
Autores principales: Chou, Han-Lin, Lin, Yi-Hsiung, Liu, Wangta, Wu, Chang-Yi, Li, Ruei-Nian, Huang, Hurng-Wern, Chou, Chi-Hsien, Chiou, Shean-Jaw, Chiu, Chien-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468447/
https://www.ncbi.nlm.nih.gov/pubmed/30884764
http://dx.doi.org/10.3390/cancers11030370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468447/
https://www.ncbi.nlm.nih.gov/pubmed/30884764
http://dx.doi.org/10.3390/cancers11030370

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