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Combination Therapy of Chloroquine and C(2)-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells

Non-small cell lung cancer (NSCLC) is a type of malignant cancer, and 85% of metastatic NSCLC patients have a poor prognosis. C(2)-ceramide induces G2/M phase arrest and cytotoxicity in NSCLC cells. In this study, the autophagy-inducing effect of C(2)-ceramide was demonstrated, and cotreatment with...

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Detalles Bibliográficos
Autores principales:	Chou, Han-Lin, Lin, Yi-Hsiung, Liu, Wangta, Wu, Chang-Yi, Li, Ruei-Nian, Huang, Hurng-Wern, Chou, Chi-Hsien, Chiou, Shean-Jaw, Chiu, Chien-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468447/ https://www.ncbi.nlm.nih.gov/pubmed/30884764 http://dx.doi.org/10.3390/cancers11030370

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