Arsenic Trioxide and (−)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling

Glioblastoma is one of the deadliest malignancies and is virtually incurable. Accumulating evidence indicates that a small population of cells with a stem-like phenotype is the major culprit of tumor recurrence. Enhanced DNA repair capacity and expression of stemness marker genes are the main charac...

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Detalles Bibliográficos
Autores principales: Linder, Benedikt, Wehle, Andrej, Hehlgans, Stephanie, Bonn, Florian, Dikic, Ivan, Rödel, Franz, Seifert, Volker, Kögel, Donat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468469/
https://www.ncbi.nlm.nih.gov/pubmed/30871073
http://dx.doi.org/10.3390/cancers11030350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468469/
https://www.ncbi.nlm.nih.gov/pubmed/30871073
http://dx.doi.org/10.3390/cancers11030350

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