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Arsenic Trioxide and (−)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling

Glioblastoma is one of the deadliest malignancies and is virtually incurable. Accumulating evidence indicates that a small population of cells with a stem-like phenotype is the major culprit of tumor recurrence. Enhanced DNA repair capacity and expression of stemness marker genes are the main charac...

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Detalles Bibliográficos
Autores principales:	Linder, Benedikt, Wehle, Andrej, Hehlgans, Stephanie, Bonn, Florian, Dikic, Ivan, Rödel, Franz, Seifert, Volker, Kögel, Donat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468469/ https://www.ncbi.nlm.nih.gov/pubmed/30871073 http://dx.doi.org/10.3390/cancers11030350

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