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Why is NMNAT Protective against Neuronal Cell Death and Axon Degeneration, but Inhibitory of Axon Regeneration?
Nicotinamide mononucleotide adenylyltransferase (NMNAT), a key enzyme for NAD(+) synthesis, is well known for its activity in neuronal survival and attenuation of Wallerian degeneration. Recent investigations in invertebrate models have, however, revealed that NMNAT activity negatively impacts upon...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468476/ https://www.ncbi.nlm.nih.gov/pubmed/30901919 http://dx.doi.org/10.3390/cells8030267 |