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Cathepsin B Is Upregulated and Mediates ECM Degradation in Colon Adenocarcinoma HT29 Cells Overexpressing Snail

During tumor development and ongoing metastasis the acquisition of mesenchymal cell traits by epithelial carcinoma cells is achieved through a programmed phenotypic shift called the epithelial-to-mesenchymal transition, EMT. EMT contributes to increased cancer cell motility and invasiveness mainly t...

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Detalles Bibliográficos
Autores principales: Kryczka, Jakub, Papiewska-Pajak, Izabela, Kowalska, M. Anna, Boncela, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468499/
https://www.ncbi.nlm.nih.gov/pubmed/30818851
http://dx.doi.org/10.3390/cells8030203