A Systematic Pan-Cancer Analysis of Genetic Heterogeneity Reveals Associations with Epigenetic Modifiers

Intratumor genetic heterogeneity (ITH) is the main obstacle to effective cancer treatment and a major mechanism of drug resistance. It results from the continuous evolution of different clones of a tumor over time. However, the molecular features underlying the emergence of genetically-distinct subc...

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Detalles Bibliográficos
Autores principales: de Matos, Mafalda Ramos, Posa, Ioana, Carvalho, Filipa Sofia, Morais, Vanessa Alexandra, Grosso, Ana Rita, de Almeida, Sérgio Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468518/
https://www.ncbi.nlm.nih.gov/pubmed/30897760
http://dx.doi.org/10.3390/cancers11030391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468518/
https://www.ncbi.nlm.nih.gov/pubmed/30897760
http://dx.doi.org/10.3390/cancers11030391

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