Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-b]furan-5,10-diones in Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is the most frequent primary malignancy of the liver and is among the top three causes of cancer-associated death worldwide. However, the clinical use of chemotherapy for HCC has been limited by various challenges, emphasizing the urgent need for novel agents with impr...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Yang, Islam, Atikul, Su, Claire J., Tikhomirov, Alexander S., Shchekotikhin, Andrey E., Chuang, Show-Mei, Chueh, Pin Ju, Chen, Yao Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468551/
https://www.ncbi.nlm.nih.gov/pubmed/30909652
http://dx.doi.org/10.3390/cancers11030420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468551/
https://www.ncbi.nlm.nih.gov/pubmed/30909652
http://dx.doi.org/10.3390/cancers11030420

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