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Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases

Neurodegenerative diseases such as Alzheimer’s disease have proven resistant to new treatments. The complexity of neurodegenerative disease mechanisms can be highlighted by accumulating evidence for a role for a growth factor, progranulin (PGRN). PGRN is a glycoprotein encoded by the GRN/Grn gene wi...

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Detalles Bibliográficos
Autores principales: Mendsaikhan, Anarmaa, Tooyama, Ikuo, Walker, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468562/
https://www.ncbi.nlm.nih.gov/pubmed/30862089
http://dx.doi.org/10.3390/cells8030230