Cargando…
Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases
Neurodegenerative diseases such as Alzheimer’s disease have proven resistant to new treatments. The complexity of neurodegenerative disease mechanisms can be highlighted by accumulating evidence for a role for a growth factor, progranulin (PGRN). PGRN is a glycoprotein encoded by the GRN/Grn gene wi...
Autores principales: | Mendsaikhan, Anarmaa, Tooyama, Ikuo, Walker, Douglas G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468562/ https://www.ncbi.nlm.nih.gov/pubmed/30862089 http://dx.doi.org/10.3390/cells8030230 |
Ejemplares similares
-
Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer’s disease and aged brains: increased levels correlate with neuropathology
por: Mendsaikhan, Anarmaa, et al.
Publicado: (2019) -
Differences in Gene Expression Profiles and Phenotypes of Differentiated SH-SY5Y Neurons Stably Overexpressing Mitochondrial Ferritin
por: Mendsaikhan, Anarmaa, et al.
Publicado: (2019) -
Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains
por: Walker, Douglas G., et al.
Publicado: (2020) -
Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin
por: Walker, Douglas G., et al.
Publicado: (2019) -
Identification of juvenility-associated genes in the mouse hepatocytes and cardiomyocytes
por: Jam, Faidruz Azura, et al.
Publicado: (2018)