Cargando…

Role of Calcium Signaling in GA101-Induced Cell Death in Malignant Human B Cells

GA101/obinutuzumab is a novel type II anti-CD20 monoclonal antibody (mAb), which is more effective than rituximab (RTX) in preclinical and clinical studies when used in combination with chemotherapy. Ca(2+) signaling was shown to play a role in RTX-induced cell death. This report concerns the effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Latour, Simon, Zanese, Marion, Le Morvan, Valérie, Vacher, Anne-Marie, Menard, Nelly, Bijou, Fontanet, Durrieu, Francoise, Soubeyran, Pierre, Savina, Ariel, Vacher, Pierre, Bresson-Bepoldin, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468563/
https://www.ncbi.nlm.nih.gov/pubmed/30832225
http://dx.doi.org/10.3390/cancers11030291