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Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy

Accumulating evidence has indicated that inflammation, oxidative stress, apoptosis, and autophagy in retinal Müller cells are involved in diabetic retinopathy (DR). Notoginsenoside R1 (NGR1), a novel saponin extracted from Panax notoginseng, posesses pharmacological properties, including treating di...

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Detalles Bibliográficos
Autores principales: Zhou, Ping, Xie, Weijie, Meng, Xiangbao, Zhai, Yadong, Dong, Xi, Zhang, Xuelian, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468581/
https://www.ncbi.nlm.nih.gov/pubmed/30832367
http://dx.doi.org/10.3390/cells8030213