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Lamina Associated Domains and Gene Regulation in Development and Cancer

The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Genomic regions contacting the NL are lamina associated domains (LADs), which contain thousands of genes that are lowl...

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Detalles Bibliográficos
Autores principales: Lochs, Silke J. A., Kefalopoulou, Samy, Kind, Jop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468596/
https://www.ncbi.nlm.nih.gov/pubmed/30901978
http://dx.doi.org/10.3390/cells8030271