Repeat Instability in the Fragile X-Related Disorders: Lessons from a Mouse Model

The fragile X-related disorders (FXDs) are a group of clinical conditions that result primarily from an unusual mutation, the expansion of a CGG-repeat tract in exon 1 of the FMR1 gene. Mouse models are proving useful for understanding many aspects of disease pathology in these disorders. There is a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Xiaonan, Gazy, Inbal, Hayward, Bruce, Pintado, Elizabeth, Hwang, Ye Hyun, Tassone, Flora, Usdin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468611/
https://www.ncbi.nlm.nih.gov/pubmed/30832215
http://dx.doi.org/10.3390/brainsci9030052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468611/
https://www.ncbi.nlm.nih.gov/pubmed/30832215
http://dx.doi.org/10.3390/brainsci9030052

Ejemplares similares