Drugging the Small GTPase Pathways in Cancer Treatment: Promises and Challenges

Small GTPases are a family of low molecular weight GTP-hydrolyzing enzymes that cycle between an inactive state when bound to GDP and an active state when associated to GTP. Small GTPases regulate key cellular processes (e.g., cell differentiation, proliferation, and motility) as well as subcellular...

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Detalles Bibliográficos
Autores principales: Prieto-Dominguez, Néstor, Parnell, Christopher, Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468615/
https://www.ncbi.nlm.nih.gov/pubmed/30884855
http://dx.doi.org/10.3390/cells8030255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468615/
https://www.ncbi.nlm.nih.gov/pubmed/30884855
http://dx.doi.org/10.3390/cells8030255

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