Lactate Activates the E2F Pathway to Promote Cell Motility by Up-Regulating Microtubule Modulating Genes

Excess lactate production due to enhanced aerobic glycolysis is characteristic of malignant cancers, which is also intimately associated with poor cancer prognoses. Although tumor-associated lactate contributes to all major steps in carcinogenesis, its action mechanism remains obscure. To understand...

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Detalles Bibliográficos
Autores principales: Jung, Yi-deun, Cho, Jung Hee, Park, Seulki, Kang, Minho, Park, Seung-jin, Choi, Dong Hee, Jeong, Moonkyung, Park, Kyung Chan, Yeom, Young Il, Lee, Dong Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468617/
https://www.ncbi.nlm.nih.gov/pubmed/30813560
http://dx.doi.org/10.3390/cancers11030274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468617/
https://www.ncbi.nlm.nih.gov/pubmed/30813560
http://dx.doi.org/10.3390/cancers11030274

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