Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores

Faithful chromosome segregation during mitosis is crucial for maintaining genome stability. The spindle assembly checkpoint (SAC) is a surveillance mechanism that ensures accurate mitotic progression. Defective SAC signaling leads to premature sister chromatid separation and aneuploid daughter cells...

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Detalles Bibliográficos
Autores principales: Dou, Zhen, Prifti, Diogjena Katerina, Gui, Ping, Liu, Xing, Elowe, Sabine, Yao, Xuebiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468716/
https://www.ncbi.nlm.nih.gov/pubmed/30909555
http://dx.doi.org/10.3390/cells8030278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468716/
https://www.ncbi.nlm.nih.gov/pubmed/30909555
http://dx.doi.org/10.3390/cells8030278

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