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Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores
Faithful chromosome segregation during mitosis is crucial for maintaining genome stability. The spindle assembly checkpoint (SAC) is a surveillance mechanism that ensures accurate mitotic progression. Defective SAC signaling leads to premature sister chromatid separation and aneuploid daughter cells...
Autores principales: | Dou, Zhen, Prifti, Diogjena Katerina, Gui, Ping, Liu, Xing, Elowe, Sabine, Yao, Xuebiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468716/ https://www.ncbi.nlm.nih.gov/pubmed/30909555 http://dx.doi.org/10.3390/cells8030278 |
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