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CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

CD44 is a multifunctional adhesion molecule typically upregulated in malignant, inflamed and injured tissues. Due to its ability to bind multiple ligands present in the tumor microenvironment, it promotes multiple cellular functions related to tumorigenesis. Recent data has shown that CD44 and its p...

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Detalles Bibliográficos
Autores principales: Härkönen, Kai, Oikari, Sanna, Kyykallio, Heikki, Capra, Janne, Hakkola, Sini, Ketola, Kirsi, Thanigai Arasu, Uma, Daaboul, George, Malloy, Andrew, Oliveira, Carla, Jokelainen, Otto, Sironen, Reijo, Hartikainen, Jaana M., Rilla, Kirsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468717/
https://www.ncbi.nlm.nih.gov/pubmed/30909497
http://dx.doi.org/10.3390/cells8030276