Rapid Generation of Long Noncoding RNA Knockout Mice Using CRISPR/Cas9 Technology

In recent years, long noncoding RNAs (lncRNAs) have emerged as multifaceted regulators of gene expression, controlling key developmental and disease pathogenesis processes. However, due to the paucity of lncRNA loss-of-function mouse models, key questions regarding the involvement of lncRNAs in orga...

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Detalles Bibliográficos
Autores principales: Hansmeier, Nils R., Widdershooven, Pia J. M., Khani, Sajjad, Kornfeld, Jan-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468733/
https://www.ncbi.nlm.nih.gov/pubmed/30678101
http://dx.doi.org/10.3390/ncrna5010012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468733/
https://www.ncbi.nlm.nih.gov/pubmed/30678101
http://dx.doi.org/10.3390/ncrna5010012

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