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NGFI-A Binding Protein 2 Promotes EGF-Dependent HNSCC Cell Invasion

NGFI-A binding protein 2 (NAB2) represses the transcriptional activation of early growth response protein-1 (EGR1), a tumor-suppressor. However, Epidermal Growth Factor (EGF) promotes tumor progression even with significant EGR1 upregulation. The molecular mechanism through which NAB2 is involved in...

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Detalles Bibliográficos
Autores principales: Kim, Jinkyung, Kang, Sung-Min, Oh, Su Young, Lee, Heon-Jin, Lee, Inhan, Hwang, Jae-Chan, Hong, Su-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468740/
https://www.ncbi.nlm.nih.gov/pubmed/30845713
http://dx.doi.org/10.3390/cancers11030315