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IL-6, IL-12, and IL-23 STAT-Pathway Genetic Risk and Responsiveness of Lymphocytes in Patients with Multiple Sclerosis

Multiple sclerosis (MS) is an immune-mediated demyelinating disease characterized by central nervous system (CNS) lymphocyte infiltration, abundant production of pro-inflammatory cytokines, and inappropriate activation of Th1 and Th17 cells, B cells, and innate immune cells. The etiology of MS is co...

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Detalles Bibliográficos
Autores principales: von Essen, Marina R., Søndergaard, Helle B., Petersen, Eva R.S., Sellebjerg, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468786/
https://www.ncbi.nlm.nih.gov/pubmed/30917537
http://dx.doi.org/10.3390/cells8030285