The Use of Pluripotent Stem Cell-Derived Organoids to Study Extracellular Matrix Development during Neural Degeneration

The mechanism that causes the Alzheimer’s disease (AD) pathologies, including amyloid plaque, neurofibrillary tangles, and neuron death, is not well understood due to the lack of robust study models for human brain. Three-dimensional organoid systems based on human pluripotent stem cells (hPSCs) hav...

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Detalles Bibliográficos
Autores principales: Yan, Yuanwei, Bejoy, Julie, Marzano, Mark, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468789/
https://www.ncbi.nlm.nih.gov/pubmed/30875781
http://dx.doi.org/10.3390/cells8030242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468789/
https://www.ncbi.nlm.nih.gov/pubmed/30875781
http://dx.doi.org/10.3390/cells8030242

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