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A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver

Obesity is frequently associated with excessive accumulation of lipids in ectopic tissue and presents a major risk factor for type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD). Diacylglycerols (DAGs) and ceramides (CERs) were identified as key players in lipid-induced insulin resis...

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Detalles Bibliográficos
Autores principales: Preuss, Christina, Jelenik, Tomas, Bódis, Kálmán, Müssig, Karsten, Burkart, Volker, Szendroedi, Julia, Roden, Michael, Markgraf, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468791/
https://www.ncbi.nlm.nih.gov/pubmed/30909521
http://dx.doi.org/10.3390/cells8030277