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Alpha6-Integrin Regulates FGFR1 Expression through the ZEB1/YAP1 Transcription Complex in Glioblastoma Stem Cells Resulting in Enhanced Proliferation and Stemness

Glioblastoma (GBM) is the most lethal primary brain tumor in adults and is known to be particularly aggressive and resistant to anti-cancer therapies, mainly due to the presence of GBM stem cells (GBMSC). By in vitro approaches supported by analysis from patients’ databases, we determined how α6-int...

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Detalles Bibliográficos
Autores principales: KOWALSKI-CHAUVEL, Aline, GOUAZE-ANDERSSON, Valerie, BARICAULT, Laurent, MARTIN, Elodie, DELMAS, Caroline, TOULAS, Christine, COHEN-JONATHAN-MOYAL, Elizabeth, SEVA, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468800/
https://www.ncbi.nlm.nih.gov/pubmed/30909436
http://dx.doi.org/10.3390/cancers11030406