Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres

High-grade glioma (HGG, WHO Grade III–IV) accounts for the majority of adult primary malignant brain tumors. Failure of current therapies to target invasive glioma cells partly explains the minimal survival advantages: invasive tumors lack easily-defined surgical margins, and are inherently more che...

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Detalles Bibliográficos
Autores principales: Pettee, Krista M., Becker, Kathryn N., Alberts, Arthur S., Reinard, Kevin A., Schroeder, Jason L., Eisenmann, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468841/
https://www.ncbi.nlm.nih.gov/pubmed/30897774
http://dx.doi.org/10.3390/cancers11030392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468841/
https://www.ncbi.nlm.nih.gov/pubmed/30897774
http://dx.doi.org/10.3390/cancers11030392

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