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Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres
High-grade glioma (HGG, WHO Grade III–IV) accounts for the majority of adult primary malignant brain tumors. Failure of current therapies to target invasive glioma cells partly explains the minimal survival advantages: invasive tumors lack easily-defined surgical margins, and are inherently more che...
Autores principales: | Pettee, Krista M., Becker, Kathryn N., Alberts, Arthur S., Reinard, Kevin A., Schroeder, Jason L., Eisenmann, Kathryn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468841/ https://www.ncbi.nlm.nih.gov/pubmed/30897774 http://dx.doi.org/10.3390/cancers11030392 |
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