Integrated Analysis of Germline and Tumor DNA Identifies New Candidate Genes Involved in Familial Colorectal Cancer

Colorectal cancer (CRC) shows aggregation in some families but no alterations in the known hereditary CRC genes. We aimed to identify new candidate genes which are potentially involved in germline predisposition to familial CRC. An integrated analysis of germline and tumor whole-exome sequencing dat...

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Detalles Bibliográficos
Autores principales: Díaz-Gay, Marcos, Franch-Expósito, Sebastià, Arnau-Collell, Coral, Park, Solip, Supek, Fran, Muñoz, Jenifer, Bonjoch, Laia, Gratacós-Mulleras, Anna, Sánchez-Rojas, Paula A., Esteban-Jurado, Clara, Ocaña, Teresa, Cuatrecasas, Miriam, Vila-Casadesús, Maria, Lozano, Juan José, Parra, Genis, Laurie, Steve, Beltran, Sergi, Castells, Antoni, Bujanda, Luis, Cubiella, Joaquín, Balaguer, Francesc, Castellví-Bel, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468873/
https://www.ncbi.nlm.nih.gov/pubmed/30871259
http://dx.doi.org/10.3390/cancers11030362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468873/
https://www.ncbi.nlm.nih.gov/pubmed/30871259
http://dx.doi.org/10.3390/cancers11030362

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