Parvovirus B19V Nonstructural Protein NS1 Induces Double-Stranded Deoxyribonucleic Acid Autoantibodies and End-Organ Damage in Nonautoimmune Mice

BACKGROUND: Viral infection is implicated in development of autoimmunity. Parvovirus B19 (B19V) nonstructural protein, NS1, a helicase, covalently modifies self double-stranded deoxyribonucleic acid (dsDNA) and induces apoptosis. This study tested whether resulting apoptotic bodies (ApoBods) contain...

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Detalles Bibliográficos
Autores principales: Puttaraksa, Kanoktip, Pirttinen, Heidi, Karvonen, Kati, Nykky, Jonna, Naides, Stanley J, Gilbert, Leona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468957/
https://www.ncbi.nlm.nih.gov/pubmed/30346568
http://dx.doi.org/10.1093/infdis/jiy614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468957/
https://www.ncbi.nlm.nih.gov/pubmed/30346568
http://dx.doi.org/10.1093/infdis/jiy614

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