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Parvovirus B19V Nonstructural Protein NS1 Induces Double-Stranded Deoxyribonucleic Acid Autoantibodies and End-Organ Damage in Nonautoimmune Mice

BACKGROUND: Viral infection is implicated in development of autoimmunity. Parvovirus B19 (B19V) nonstructural protein, NS1, a helicase, covalently modifies self double-stranded deoxyribonucleic acid (dsDNA) and induces apoptosis. This study tested whether resulting apoptotic bodies (ApoBods) contain...

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Detalles Bibliográficos
Autores principales:	Puttaraksa, Kanoktip, Pirttinen, Heidi, Karvonen, Kati, Nykky, Jonna, Naides, Stanley J, Gilbert, Leona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468957/ https://www.ncbi.nlm.nih.gov/pubmed/30346568 http://dx.doi.org/10.1093/infdis/jiy614

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