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Osteosarcoma Therapy: Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation (Adv. Sci. 8/2019)

In article number 1801233, Jianxun Ding, Yingqi Hua, Zhengdong Cai, and co‐workers report a combination strategy for improving the efficacy of fullerene C60 nanocrystals in anti‐osteosarcoma therapy. Inhibition of CaMKIIα activity by KN‐93 promotes excessive autophagosome accumulation and autophagic...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Wang, Hongsheng, Hu, Yi, Zhang, Yu Shrike, Wen, Longping, Yin, Fei, Wang, Zhuoying, Zhang, Yingchao, Li, Suoyuan, Miao, Yanyan, Lin, Binhui, Zuo, Dongqing, Wang, Gangyang, Mao, Min, Zhang, Tao, Ding, Jianxun, Hua, Yingqi, Cai, Zhengdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468958/
http://dx.doi.org/10.1002/advs.201970051