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A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer

Programmed cell death protein 1 (PD-1) and its ligand PD-L1 blockade have been identified to target immune checkpoints to treat human cancers with durable clinical benefit. Several studies reveal that the response to PD-1-PD-L1 blockade might correlate with PD-L1 expression levels in tumor cells. Ho...

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Detalles Bibliográficos
Autores principales: Zhu, Junlan, Li, Yang, Luo, Yisi, Xu, Jiheng, Liufu, Huating, Tian, Zhongxian, Huang, Chao, Li, Jingxia, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468999/
https://www.ncbi.nlm.nih.gov/pubmed/30871066
http://dx.doi.org/10.3390/cancers11030349