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Transcriptional positive cofactor 4 promotes breast cancer proliferation and metastasis through c-Myc mediated Warburg effect

BACKGROUND: The human positive cofactor 4 (PC4) is initially identified as a transcriptional cofactor and has an important role in embryonic development and malignant transformation. However, the clinical significance and the molecular mechanisms of PC4 in breast cancer development and progression a...

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Detalles Bibliográficos
Autores principales: Luo, Peng, Zhang, Chi, Liao, Fengying, Chen, Long, Liu, Zhenyu, Long, Lei, Jiang, Zhongyong, Wang, Yawei, Wang, Ziwen, Liu, Zujuan, Miao, Hongming, Shi, Chunmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469038/
https://www.ncbi.nlm.nih.gov/pubmed/30992017
http://dx.doi.org/10.1186/s12964-019-0348-0