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Microencapsulation of Salmonella-Specific Bacteriophage Felix O1 Using Spray-Drying in a pH-Responsive Formulation and Direct Compression Tableting of Powders into a Solid Oral Dosage Form

The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high dos...

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Detalles Bibliográficos
Autores principales: Vinner, Gurinder K., Rezaie-Yazdi, Zahra, Leppanen, Miika, Stapley, Andrew G.F., Leaper, Mark C., Malik, Danish J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469172/
https://www.ncbi.nlm.nih.gov/pubmed/30909381
http://dx.doi.org/10.3390/ph12010043