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Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology

BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by the deposition of extracellular fibrillar amyloid β (fΑβ) and the intracellular accumulation of neurofibrillary tangles. As AD progresses, Aβ drives a robust and prolonged inflammatory response via it...

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Detalles Bibliográficos
Autores principales: El Hajj, Hassan, Savage, Julie C., Bisht, Kanchan, Parent, Martin, Vallières, Luc, Rivest, Serge, Tremblay, Marie-Ève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469225/
https://www.ncbi.nlm.nih.gov/pubmed/30992040
http://dx.doi.org/10.1186/s12974-019-1473-9