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Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology
BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by the deposition of extracellular fibrillar amyloid β (fΑβ) and the intracellular accumulation of neurofibrillary tangles. As AD progresses, Aβ drives a robust and prolonged inflammatory response via it...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469225/ https://www.ncbi.nlm.nih.gov/pubmed/30992040 http://dx.doi.org/10.1186/s12974-019-1473-9 |