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2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, (18)F-Labeling and Preclinical PET Imaging

The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar derivatives—mimicking nucleosides—have proven the...

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Detalles Bibliográficos
Autores principales: Maier, Florian C., Schweifer, Anna, Damaraju, Vijaya L., Cass, Carol E., Bowden, Gregory D., Ehrlichmann, Walter, Kneilling, Manfred, Pichler, Bernd J., Hammerschmidt, Friedrich, Reischl, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469291/
https://www.ncbi.nlm.nih.gov/pubmed/30781409
http://dx.doi.org/10.3390/ph12010031